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بلال عبدالعزيز الحسين
• قسم الصيدلة السريرية - عضو هيئة تدريس

  • الدكـتوراة في صيدله من جامعة جورجيا, 2013
  • ماجستير في صيدله من جامعة العلوم والتكنولوجيا الاردنيه, 2002
  • بكالوريوس في صيدله من جامعة العلوم والتكنولوجيا الاردنيه, 2000

    Publications
  • Kochuparambil, Samith T and Al-Husein, Belal and Goc, Anna and Soliman, Sahar and Somanath, Payaningal R, "Anticancer efficacy of simvastatin on prostate cancer cells and tumor xenografts is associated with inhibition of Akt and reduced prostate-specific antigen expression," Journal of Pharmacology and Experimental Therapeutics, vol. 336, no. , pp. 496-505, 2011, ASPET
  • Kichina, Julia V and Goc, Anna and Al-Husein, Belal and Somanath, Payaningal R and Kandel, Eugene S, "PAK1 as a therapeutic target," Expert opinion on therapeutic targets, vol. 14, no. , pp. 703-725, 2010, Taylor \& Francis
  • Goc, Anna and Al-Husein, Belal and Kochuparambil, Samith T and Liu, Junxiu and Heston, Warren WD and Somanath, Payaningal R, "PI3 kinase integrates Akt and MAP kinase signaling pathways in the regulation of prostate cancer," International journal of oncology, vol. 38, no. , pp. 267-277, 2010, Spandidos Publications
  • Al-Husein, Belal and Abdalla, Maha and Trepte, Morgan and DeRemer, David L and Somanath, Payaningal R, "Antiangiogenic therapy for cancer: an update," Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, vol. 32, no. , pp. 1095-1111, 2012
  • Goc, Anna and Kochuparambil, Samith T and Al-Husein, Belal and Al-Azayzih, Ahmad and Mohammad, Shuaib and Somanath, Payaningal R, "Simultaneous modulation of the intrinsic and extrinsic pathways by simvastatin in mediating prostate cancer cell apoptosis," BMC cancer, vol. 12, no. , pp. 0-0, 2012, BioMed Central
  • Goc, Anna and Al-Azayzih, Ahmad and Abdalla, Maha and Al-Husein, Belal and Kavuri, Sravankumar and Lee, Jeffrey and Moses, Kelvin and Somanath, Payaningal R, "P21 activated kinase-1 (Pak1) promotes prostate tumor growth and microinvasion via inhibition of transforming growth factor $\beta$ expression and enhanced matrix metalloproteinase 9 secretion," Journal of Biological Chemistry, vol. 288, no. , pp. 3025-3035, 2013, American Society for Biochemistry and Molecular Biology
  • Kaddour-Djebbar, Ismail and Choudhary, Vivek and Lakshmikanthan, Vijayabaskar and Shirley, Robert and El Gaish, Manal and Al-Shabrawey, Mohamed and Al-Husein, Belal and Zhong, Roger and Davis, Michael and Dong, Zheng and others, "Diltiazem enhances the apoptotic effects of proteasome inhibitors to induce prostate cancer cell death," Journal of Pharmacology and Experimental Therapeutics, vol. 341, no. , pp. 646-655, 2012, American Society for Pharmacology and Experimental Therapeutics
  • Kochuparambil, Samith Thomas and Al-Husein, Belal and Goc, Anna and Terris, Martha and Somanath, Payaningal R, "410 ANTI-CANCER EFFICACY OF SIMVASTATIN ON PROSTATE CANCER CELLS AND TUMOR XENOGRAFTS IS MEDIATED THROUGH INHIBITION OF AKT," The Journal of Urology, vol. 185, no. , pp. -1--1, 2011, Wolters Kluwer Philadelphia, PA
  • AL-Husein, Belal and Goc, Anna and Somanath, Payaningal R, "Suppression of interactions between prostate tumor cell-surface integrin and endothelial ICAM-1 by simvastatin inhibits micrometastasis," Journal of cellular physiology, vol. 228, no. , pp. 2139-2148, 2013
  • Al-Azzam, Sayer I and Al-Husein, Belal A and Alzoubi, Firas and Masadeh, Majed M and others, "Self-medication with antibiotics in Jordanian population," International journal of occupational medicine and environmental health, vol. 20, no. , pp. 0-0, 2007, Nofer Institute of Occupational Medicine
  • Al-Azzam, Sayer I and Al-Husein, Belal A and Abu-Dahoud, Essam Y and Dawoud, Tasneem H and Al-Momany, Ena'am M, "Etiologies of acute renal failure in a sample of hospitalized Jordanian patients," Renal failure, vol. 30, no. , pp. 373-376, 2008, Taylor \& Francis
  • Al-Azzam, Sayer I and Abu-dahoud, Essam Y and El-khatib, Hasan A and Dawoud, Tasneem H and Al-Husein, Belal A, "Etiologies of chronic renal failure in Jordanian population," Journal of Nephrology, vol. 20, no. , pp. 336-339, 2007, Rome: Acta Medica
  • Al-Azzam, Sayer and Alzoubi, Karem H and Ayoub, Nehad M and Khader, Yousef Saleh and Karasneh, Reema A and Al-Husein, Belal A and Al-Horani, Mohammad Ali S, "An audit on public awareness of depression symptoms in Jordan," International journal of occupational medicine and environmental health, vol. 26, no. , pp. 545-554, 2013, Springer Vienna
  • Mhaidat, NM and Alzoubi, KH and Al-Sweedan, S and Alhusein, BA, "Prevalence of depression among cancer patients in Jordan: a national survey," Supportive care in cancer, vol. 17, no. , pp. 0-0, 2009, Springer-Verlag
  • Goc, Anna and Al-Husein, Belal and Katsanevas, Katerina and Steinbach, Alison and Lou, Uvette and Sabbineni, Harika and DeRemer, David L and Somanath, Payaningal R, "Targeting Src-mediated Tyr216 phosphorylation and activation of GSK-3 in prostate cancer cells inhibit prostate cancer progression in vitro and in vivo," Oncotarget, vol. 5, no. , pp. 0-0, 2014, Impact Journals, LLC
  • Kochuparambil, ST and Al-Husein, B and Goc, A and Mohammad, S and Terris, MK and Samuel, TA and Coleman, TA and Shenoy, SPR, "Effects of simvastatin and docetaxel on different pathways in the regulation of prostate and breast cancer cell survival.," Journal of Clinical Oncology, vol. 29, no. , pp. -1--1, 2011, American Society of Clinical Oncology
  • Lee, Jeffrey and Moses, Kelvin and Somanath, Payaningal R, "Anna Goc1, 2, Ahmad Al-Azayzih1, 2, Maha Abdalla1, 2, Belal Al-Husein1, 2, Sravankumar Kavuri2, 3," , vol. , no. , pp. 0-0, 2012
  • Khabour, Omar F and Alzoubi, Karem H and Abu Thiab, Tuqa M and Al-Husein, Belal A and Eissenberg, Thomas and Shihadeh, Alan Louis, "Changes in the expression and protein level of matrix metalloproteinases after exposure to waterpipe tobacco smoke," Inhalation toxicology, vol. 27, no. , pp. 689-693, 2015, Informa Healthcare
  • Mhaidat, Nizar M and Al-Husein, Belal A and Alzoubi, Karem H and Hatamleh, Dima I and Khader, Youcef and Matalqah, Sinaa and Albsoul, Abla, "Knowledge and awareness of colorectal cancer early warning signs and risk factors among university students in Jordan," Journal of Cancer Education, vol. 33, no. , pp. 448-456, 2018, Springer US
  • Doa?a, GF Al- and Al-Husein, Belal AA and Qasaimeh, Ghazi Raji, "A mini-review of c-Met as a potential therapeutic target in melanoma," Biomedicine \& Pharmacotherapy, vol. 88, no. , pp. 194-202, 2017, Elsevier Masson
  • Alshogran, Osama Y and Al-Obaidi, Esra'a F and Al-Husein, Belal A and Oweis, Ashraf O, "Evaluation of the Effect of Uremic Serum on Hepatic Reductase Functional Expression," Drug metabolism letters, vol. 12, no. , pp. 75-81, 2018, Bentham Science Publishers
  • Kochuparambil, Samith Thomas and Al-Husein, Belal and Goc, Anna and Terris, Martha and Somanath, Payaningal R, "410 ANTI-CANCER EFFICACY OF SIMVASTATIN ON PROSTATE CANCER CELLS AND TUMOR XENOGRAFTS IS MEDIATED THROUGH INHIBITION OF AKT," JOURNAL OF UROLOGY, vol. 200, no. , pp. -1--1, 2018, Elsevier
  • Al-Husein, Belal A and Bara?Dawah, Saleem Bani-Hani and Al Bashir, Samir M and Al-Sawalmeh, Khaled M and Ayoub, Nehad M, "Immunomodulatory effect of statins on Regulatory T Lymphocytes in human colorectal cancer is determined by the stage of disease," Oncotarget, vol. 9, no. , pp. 0-0, 2018, Impact Journals, LLC
  • Al-Husein, Belal A and Al-Azzam, Sayer I and Alzoubi, Karem H and Khabour, Omar F and Nusair, Mohammad B and Alzayadeen, Samar, "Investigating the effect of demographics, clinical characteristics, and polymorphism of MDR-1, CYP1A2, CYP3A4, and CYP3A5 on clopidogrel resistance," Journal of cardiovascular pharmacology, vol. 72, no. , pp. 296-302, 2018, LWW
  • Banihani, Saleem A and Shuaibu, Shuaibu M and Al-Husein, Belal A and Makahleh, Seham S, "Fresh pomegranate juice decreases fasting serum erythropoietin in patients with type 2 diabetes," International journal of food science, vol. 2019, no. , pp. 0-0, 2019, Hindawi
  • Goc, Anna and Kochuparambil, Samith T and Al-Husein, Belal and Al-Azayzih, Ahmad and Mohammad, Shuaib and Somanath, Payaningal R, "Simultaneous modulation of the intrinsic and extrinsic pathways by," , vol. , no. , pp. 0-0,
  • Muflih, Suhaib and Al-Husein, Belal A and Karasneh, Reema and Alzoubi, Karem H, "Physicians? Attitudes and Ethical Obligations to Pharmacogenetic Testing," Journal of Multidisciplinary Healthcare, vol. 13, no. , pp. 0-0, 2020, Dove Press
  • Ayoub, Nehad M and Ibrahim, Dalia R and Alkhalifa, Amer E and Al-Husein, Belal A, "Crizotinib induced antitumor activity and synergized with chemotherapy and hormonal drugs in breast cancer cells via downregulating MET and estrogen receptor levels," Investigational New Drugs, vol. , no. , pp. 1-12, 2020, Springer US
  • Shenoy, Somanath and Kochuparambil, Samith T and Al-Husein, Belal and Goc, Anna, "Statins for prostate cancer: a friend, a foe or neither," , 2011, pp. -1--1, SPANDIDOS PUBL LTD POB 18179, ATHENS, 116 10, GREECE
  • Al-Husein, Belal Abdelaziz Abdeljalil, Molecular mechanisms regulating simvastatin-mediated inhibition of prostate cancer cellular functions in vitro and tumor growth in vivo, , 2013
  • Kochuparambil, Samith T and Al-Husein, Belal and Goc, Anna and Soliman, Sahar and Choudhary, Mrunal and Liu, Junxiu and Somanath, Payaningal R, Abstract B47: Pleiotropic effects of simvastatin on prostate tumor growth and metastasis, American Association for Cancer Research, 2010
  • Al-Husein, Belal, Immunomodulatory effect of statins on Tregs within human colorectal cancer is determined by the stage of disease, American Association for Cancer Research, 2018
  • Al-Husein, Belal, Interaction of atorvastatin and CX3CR1-fractalkine in androgen-dependent prostate cancer cells: Effect on PI3K pathway, American Association for Cancer Research, 2019
  • "A mini-review of c-Met as a potential therapeutic target in melanoma", Biomedicine & pharmacotherapy
  • "Adherence and utilization of short-term antibiotics: Randomized controlled study", PloS one
  • "Crizotinib induced antitumor activity and synergized with chemotherapy and hormonal drugs in breast cancer cells via downregulating MET and estrogen receptor levels", Investigational New Drugs
  • "Enzymatic bioactive peptides from sonicated whey proteins of camel milk: Impacts of nanopeptides on structural properties, antioxidant activity and inhibitory activity of alpha-amylase and ACE", International Journal of Dairy Technology
  • "Investigating the Effect of Demographics, Clinical Characteristics, and Polymorphism of MDR-1, CYP1A2, CYP3A4, and CYP3A5 on Clopidogrel Resistance.", Journal of Cardiovascular Pharmacology
  • "Involvement and possible role of transglutaminases 1 and 2 in mediating fibrotic signalling, collagen cross-linking and cell proliferation in neonatal rat ventricular fibroblasts", PLOS ONE
  • "Knowledge and Awareness of Colorectal Cancer Early Warning Signs and Risk Factors among University Students in Jordan", Journal of Cancer Education
  • "Photolytic Controlled Release Formulation of Methotrexate Loaded in Chitosan/TiO2 Nanoparticles for Breast Cancer", Pharmaceuticals
  • "Physicians? Attitudes and Ethical Obligations to Pharmacogenetic Testing", Journal of Multidisciplinary Healthcare
  • "Preparation of Modified Chitosan-Based Nanoparticles for Efficient Delivery of Doxorubicin and/or Cisplatin to Breast Cancer Cells", Current Cancer Drug Targets
  • "Prevalence of Medication Associated with QTc Prolongation Used Among Critically Ill Patients", Vascular Health and Risk Management
  • "Rapid high performance liquid chromatography method for erlotinib quantification in vitro: Application to study the effect of resveratrol on metabolism and cellular uptake of erlotinib", Fundamental and Clinical Pharmacology
  • "Students? experiences and attitudes toward a newly developed simulation-based pharmaceutical care clinical rotation: A pre-post study design", Saudi Pharmaceutical Journal
  • Assistant Dean, Assistant Dean, Sep 2020 - Sep 2021
  • Assistant Dean, Assistant Dean, Sep 2019 - Sep 2020
  • Faculty Member, Department of Clinical Pharmacy, Sep 2013 - Present
  • Full-time Lecturer, Department of Clinical Pharmacy, Apr 2013 - Sep 2013
  • ADVANCED THERAPEUTICS
  • CLINICAL CASES
  • CLINICAL PHARMACOKINETIS (FOR PHARM D STUDENTS)
  • CLINICAL SEMINAR (1 ) (FOR PHD STUDENTS)
  • CLINICAL SEMINAR (2) (FOR PHD STUDENTS)
  • CLINICAL TRAINING : PHARMACEUTICAL RESEARCH (FOR PHARM.D STUDENTS)
  • CLINICAL TRAINING :PAEDIATRICS (FOR PHARM.D STUDENTS)
  • CLINICAL TRAINING: CRITICAL CARE (FOR PHARM.D STUDENTS)
  • CLINICAL TRAINING: ONCOLOGY (FOR PHARM D STUDENTS)
  • CLINICAL TRAINING: PEDIATRIC ONCOLOGY
  • CLINICAL TRAINING:NEONATAL INTENSIVE CARE
  • COMMUNITY PHARMACY (FOR PHARM.D STUDENTS)
  • COMPREHENSIVE THERAPEUTICS
  • Clinical Seminar (for Pharm D students)
  • Clinical Training: Oncology (for Pharm D students)
  • DRUG INFORMATION RESOURCES
  • IMMUNOLOGY AND VACCINES
  • INTRODUCTION TO THERAPEUTICS (FOR PHARMD STUDENTS)
  • Immunology and Vaccines (for Pharm D students)
  • PHARMACEUTICAL PRACTICAL TRAINING
  • PHARMACOLOGY (3)
  • PHARMACOLOGY 3
  • PRINCIPLES OF EXPERIMENTAL THERAPEUTICS
  • Pharmacology 3
  • SEMINAR
  • THERAPEUTICS 1
  • THERAPEUTICS-CARDIOVASCULAR SYSTEM (FOR PHARM D STUDENTS)
  • THERAPEUTICS-COMPREHENSIVE (FOR PHARM.D STUDENTS)
  • THERAPEUTICS-IMMUNOLOGY, HEMATOLOGY AND ONCOLOGY (FOR PHARM.D STUDENTS)
  • THERAPEUTICS-IMMUNOLOGY, HEMATOLOGY AND ONCOLOGY (FOR PHARM.D STUDENTS)
  • THERAPEUTICS-PAEDIATRIC HEALTH (FOR PHRM.D STUDENTS)
  • Therapeutics- Immunology, Hematology and Oncology (for Pharm D students) students)