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buthina abdallah al-oudat
• Department of Medicinal Chemistry and Pharmacognosy - Faculty Member

  • Ph.D. of Medicinal Chemistry and Drug Discovery from The University of toledo, 2011
  • Bsc. of Chemistry from Jordan University of Science and Technology, 2003

    Publications
  • Al-Oudat B, Salyer A, , "3'-Modified oligodeoxyribonucleotides for the study of 2-deoxyribose damage in DNA," Bioorg Med Chem Lett. , vol. 23, no. 3, pp. 854-859, 2013
  • Audat SA, Love CT, , "Synthesis of C3' modified nucleosides for selective generation of the C3'-deoxy-3'-thymidinyl radical: a proposed intermediate in LEE induced DNA damage," J Org Chem., vol. 77, no. 8, pp. 3829-3837, 2012
  • Qosay Al-Balas, Mohammad Hassan, Buthina Al-Oudat,  Hassan Alzoubi, Nizar Mhaidat  and Ammar Almaaytah , "Generation of the First Structure-Based Pharmacophore Model Containing a Selective ?Zinc Binding Group? Feature to Identify Potential Glyoxalase-1 Inhibitors ," Molecules, vol. 17, no. , pp. 13740-13758, 2012
  • "Design, Synthesis and Biological Evaluation of 1,4-Benzenesulfonamide Derivatives as Glyoxalase I Inhibitors", Drug Design, Development and Therapy
  • "Design, synthesis and biological evaluation of novel glyoxalase I inhibitors possessing diazenylbenzenesulfonamide moiety as potential anticancer agents", Bioorganic & Medicinal Chemistry
  • "Design, synthesis, and biologic evaluation of novel chrysin derivatives as cytotoxic agents and caspase-3/7 activators", Drug Design, Development and Therapy
  • "Design, synthesis, and biological evaluation of SMYD3 inhibitors possessing N-thiazole benzenesulfonamide moiety as potential anti-cancer agents", Journal of Saudi Chemical Society
  • "Identification of Human Leukotriene A4 Hydrolase Inhibitors Using Structure-Based Pharmacophore Modeling and Molecular Docking", Molecules
  • "Lead Optimization and Biological Evaluation of Diazenylbenzenesulfonamides Inhibitors Against Glyoxalase-I Enzyme as Potential Anticancer Agents", Bioorganic Chemistry
  • "Novel Chrysin-De-Allyl PAC-1 Hybrid Analogues as Anticancer Compounds Design, Synthesis, and Biological Evaluation", Molecules
  • "Structural optimization and biological evaluation of quinoline/ naphthalene-based glyoxalase-I inhibitors as anti-cancer candidates", MEDICINAL CHEMISTRY RESEARCH
  • Deputy Head of Department, Department of Medicinal Chemistry and Pharmacognosy, Sep 2013 - Sep 2014
  • Faculty Member, Department of Medicinal Chemistry and Pharmacognosy, Mar 2012 - Present
  • ADVANCED ORGANIC SYNTHESIS
  • CHEMISTRY OF HETEROCYCLIC
  • MEDICINAL CHEMISTRY (1)
  • MEDICINAL CHEMISTRY (2)
  • MEDICINAL CHEMISTRY LAB
  • MEDICINAL CHEMISTRY( 4)
  • ORGANIC SYNTHESIS RESEACH LABORATORY
  • PHARMACEUTICAL INSTRUMENTAL ANALYSIS LAB
  • PHARMACEUTICAL ORGANIC CHEMISTRY
  • Pharmaceutical Organic Chemistry (for Pharm D students)
  • SELECTED TOPICS ( 1)
  • Pharmaceutical Organic Chemistry
  • Heterocyclic Chemistry