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aref louai zayed
• Department of Medicinal Chemistry and Pharmacognosy - Faculty Member

  • Ph.D. of Pharmacy from Loughbrough University, 2012
  • Msc. of Pharmacy from Loughbrough University, 2005
  • Bsc. of Pharmacy from Jordan University of Science and Technology, 1999

    Publications
  • Kuresh A. Youdim, Aref Zayed, Maurice Dickins, Alex Phipps, Michelle Griffiths, Amanda Darekar, Ruth Hyland, Odette Fahmi, Susan Hurst, David R. Plowchalk, Jack Cook, Feng Guo, R. Scott Obach , "Application of CYP3A4 in vitro data to predict clinical drug-drug interactions: predictions of compounds as objects of interaction," British Journal of Clinical Pharmacology, vol. 65, no. 5, pp. 680-692, 2008
  • Aref Zayed, Tamer Shoeib, Sarah E Taylor, George D D Jones, Anne L Thomas, Joanna P Wood, Helen J Reid, Barry L Sharp, "Determination of Pt-DNA adducts and the sub-cellular distribution of Pt in human cancer cell lines and the leukocytes of cancer patients, following mono- or combination treatments, by ICPMS," International Journal of Mass Spectrometry, vol. 307, no. 1-3, pp. 70-78, 2011
  • Aref Zayed, George D. D. Jones, Helen J. Reid, Tamer Shoeib,Sarah E. Taylor, Anne L. Thomas, Joanna P. Wood ,Barry L. Sharp , "Speciation of Oxaliplatin Adducts with DNA Nucleotides," Metallomics, vol. 3, no. 10, pp. 991-1000, 2011
  • "Biochemical evaluation of selected grape varieties (Vitis vinifera L.) grown in Jordan and in vitro evaluation of grape seed extract on human prostate cancer cells", Food Bioscience
  • "Enhancement of the dissolution and bioavailability from freeze-dried powder of a hypocholesterolemic drug in the presence of Soluplus", Powder Technology
  • "HPLC methods for studying pharmacokinetics of tivozanib and in vitro metabolic interaction with dexamethasone in rat", Journal of Pharmaceutical and Biomedical Analysis
  • "HPLC with Fluorescence and Photodiode Array Detection for Quantifying Capmatinib in Biological Samples: Application to In Vivo and In Vitro Studies", Molecules
  • "High Performance Liquid Chromatography (HPLC) with Fluorescence Detection for Quantification of Steroids in Clinical, Pharmaceutical, and Environmental Samples: A Review", Molecules
  • "Identification of Human Leukotriene A4 Hydrolase Inhibitors Using Structure-Based Pharmacophore Modeling and Molecular Docking", Molecules
  • "Rapid high performance liquid chromatography method for erlotinib quantification in vitro: Application to study the effect of resveratrol on metabolism and cellular uptake of erlotinib", Fundamental and Clinical Pharmacology
  • "Simultaneous determination of warfarin and 7-hydroxywarfarin in rat plasma by HPLC-FLD ", Acta Pharmaceutica
  • "The effect of grape seed and green tea extracts on the pharmacokinetics of imatinib and its main metabolite, N- desmethyl imatinib, in rats", BMC Pharmacology and Toxicology
  • Faculty Member, Department of Medicinal Chemistry and Pharmacognosy, Sep 2014 - Present
  • Full-time Lecturer, Department of Medicinal Chemistry and Pharmacognosy, Sep 2013 - Sep 2014
  • Analytical Manager, PRU, Jordan, Jan 2007- Jan 2008
  • Analytical Scientist , GlaxoSmithKline (GSK- Europe), United Kingdom, Jan 2005- Jan 2006
  • Analytical Scientist , Pfizer R & D , United Kingdom, Jan 2004- Jan 2005
  • ANALYTICAL TECHNIQUES IN DRUG DISCOVERY
  • CHROMATOGRAPHY
  • COMMUNITY PHARMACY (FOR PHARM.D STUDENTS)
  • INSTRUMENTAL ANALYSIS
  • PHARMACEUTICAL PRACTICAL TRAINING
  • PHARMACEUTICAL ANALYTICAL CHEMISTRY
  • PHARMACEUTICAL ANALYTICAL CHEMISTRY & INSTRUMENTAL ANALYSIS LAB
  • PHARMACEUTICAL INSTRUMENTAL ANALYSIS
  • PHARMACEUTICAL INSTRUMENTAL ANALYSIS LAB
  • Pharmaceutical Instrumental Analysis (for Pharm D students)
  • RESEARCH METHODOLOGY
  • SELECTED TOPICS ( 1)
  • SELECTED TOPICS ( 2)
  • SPECIAL TOPICS (B)
  • SPECIAL TOPICS (C)