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• قسم الكيمياء الطبيه والعقاقير - عضو هيئة تدريس

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قسم الكيمياء الطبيه والعقاقير
alzayed@just.edu.jo

Website

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Google Scholar

الدكـتوراة في صيدله من جامعة لفبرة, 2012
ماجستير في صيدله من جامعة لفبرة, 2005
بكالوريوس في صيدله من جامعة العلوم والتكنولوجيا الاردنيه, 1999

Publications

Kuresh A. Youdim, Aref Zayed, Maurice Dickins, Alex Phipps, Michelle Griffiths, Amanda Darekar, Ruth Hyland, Odette Fahmi, Susan Hurst, David R. Plowchalk, Jack Cook, Feng Guo, R. Scott Obach , "Application of CYP3A4 in vitro data to predict clinical drug-drug interactions: predictions of compounds as objects of interaction," British Journal of Clinical Pharmacology, vol. 65, no. 5, pp. 680-692, 2008
Aref Zayed, Tamer Shoeib, Sarah E Taylor, George D D Jones, Anne L Thomas, Joanna P Wood, Helen J Reid, Barry L Sharp, "Determination of Pt-DNA adducts and the sub-cellular distribution of Pt in human cancer cell lines and the leukocytes of cancer patients, following mono- or combination treatments, by ICPMS," International Journal of Mass Spectrometry, vol. 307, no. 1-3, pp. 70-78, 2011
Aref Zayed, George D. D. Jones, Helen J. Reid, Tamer Shoeib,Sarah E. Taylor, Anne L. Thomas, Joanna P. Wood ,Barry L. Sharp , "Speciation of Oxaliplatin Adducts with DNA Nucleotides," Metallomics, vol. 3, no. 10, pp. 991-1000, 2011
"Design, synthesis and biological evaluation of benzimidazole/bis-imine derivatives as glyoxalase I inhibitors", Medicinal Chemistry Research

Buthina Abdallah Saleh Al-Oudat, Suaad Abdallah Saleh Audat, Nizar Ali Ahmad Al-Shar'I, Qosay Ali Elayyan Al-Balas, Hana'A Jaradat, Lara Ishaq Issa Alfakhori, Aref Louai Aref Zayed

06/04/2025
"Rapid and sensitive HPLC with fluorescence detection method for quantifying selpercatinib in liver microsomes and rat plasma: Implications for drug-drug interaction studies", Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Aref Louai Aref Zayed, Aysheh Mohammad Samih Alshekhhossin, Omar Molham Jamal Al Kilani, Sana'A Ahmad Mohammad Jaber, Leen Loai Ahmad Dawood, Jomana Abd Alhakeem Hussen Al Hroot, Kawthar Zeyad Mohammad Alzarieni

27/02/2025
"Structural optimization and biological evaluation of quinoline/ naphthalene-based glyoxalase-I inhibitors as anti-cancer candidates", MEDICINAL CHEMISTRY RESEARCH

Buthina Abdallah Saleh Al-Oudat, Bushra Suleiman Abdulqader Abualfool, Suaad Abdallah Saleh Audat, Nizar Ali Ahmad Al-Shar'I, Qosay Ali Elayyan Al-Balas, Aref Louai Aref Zayed

30/07/2024
"Development of a Rapid HPLC-Fluorescence Method for Monitoring Warfarin Metabolites Formation: In-vitro Studies for Evaluating the Effect of Piperine on Warfarin Metabolism and Plasma Coagulation", Heliyon

Aref Louai Aref Zayed, Mohammad Majed Abed Hadieh, Jomana Abd Alhakeem Hussen Al Hroot, Sana'A Ahmad Mohammad Jaber, Fatima Jaser Hussien Hameedat

15/05/2024
"Characterization of a novel natural cellulosic fiber obtained from the fruit of Tipuana tipu", Biomass conversion and biorefinery

Kawthar Zeyad Mohammad Alzarieni, Omymah Marwan Adel Al Zoubi, Abeer Ahmad Mohammad Jaber, Aref Louai Aref Zayed

19/02/2024
"Rapid high performance liquid chromatography method for erlotinib quantification in vitro: Application to study the effect of resveratrol on metabolism and cellular uptake of erlotinib", Fundamental and Clinical Pharmacology

Aref Louai Aref Zayed, Jomana Abd Alhakeem Hussen Al Hroot, Belal Abdelaziz Abdeljalil Al-Husein

04/05/2023
"HPLC methods for studying pharmacokinetics of tivozanib and in vitro metabolic interaction with dexamethasone in rat", Journal of Pharmaceutical and Biomedical Analysis

Aref Louai Aref Zayed, Ghuroob Nour Aldeen Badi Hamadneh, Jomana Abd Alhakeem Hussen Al Hroot, Sana'A Ahmad Mohammad Jaber

26/04/2023
"HPLC with Fluorescence and Photodiode Array Detection for Quantifying Capmatinib in Biological Samples: Application to In Vivo and In Vitro Studies", Molecules

Aref Louai Aref Zayed, Sana'A Ahmad Mohammad Jaber, Jomana Abd Alhakeem Hussen Al Hroot, Sahar Saleh Mohammed Hawamdeh, Nehad M. M. Ayoub

05/12/2022
"High Performance Liquid Chromatography (HPLC) with Fluorescence Detection for Quantification of Steroids in Clinical, Pharmaceutical, and Environmental Samples: A Review", Molecules

Fatima Jaser Hussien Hameedat, Sahar Saleh Mohammed Hawamdeh, Soraya Ma'Moun Othman Alnabulsi, Aref Louai Aref Zayed

06/03/2022
"The effect of grape seed and green tea extracts on the pharmacokinetics of imatinib and its main metabolite, N- desmethyl imatinib, in rats", BMC Pharmacology and Toxicology

Ruba Salah Abdulrazeq Darweesh, Tamam Mohammad Murshed El-Elimat, Aref Louai Aref Zayed, Tareq N. J Khamis, Wahby Mohammed Ahmed Ba Baresh, Ahmed Hesham Ahmed Al Sharie

31/10/2020
"Identification of Human Leukotriene A4 Hydrolase Inhibitors Using Structure-Based Pharmacophore Modeling and Molecular Docking", Molecules

Suaad Abdallah Saleh Audat, Nizar Ali Ahmad Al-Shar'I, Buthina Abdallah Saleh Al-Oudat, Aref Louai Aref Zayed, Qosay Ali Elayyan Al-Balas

19/06/2020
"Simultaneous determination of warfarin and 7-hydroxywarfarin in rat plasma by HPLC-FLD ", Acta Pharmaceutica

Aref Louai Aref Zayed, Wahby Mohammed Ahmed Ba Baresh, Ruba Salah Abdulrazeq Darweesh, Tamam Mohammad Murshed El-Elimat

14/09/2019
"Biochemical evaluation of selected grape varieties (Vitis vinifera L.) grown in Jordan and in vitro evaluation of grape seed extract on human prostate cancer cells", Food Bioscience

Tamam Mohammad Murshed El-Elimat, Bara Ahmad Ali Jarwan, Aref Louai Aref Zayed, Ahmed Yusuf Ahmed Alhusban

15/06/2018
"Enhancement of the dissolution and bioavailability from freeze-dried powder of a hypocholesterolemic drug in the presence of Soluplus", Powder Technology

Mai Subhi Abdalrazaq Khanfar, Bashar Mohammad Yousef Altaani, Mo'Tasem Mohamed Sa'Id Alsmadi, Aref Louai Aref Zayed

23/01/2018

Faculty Member, Department of Medicinal Chemistry and Pharmacognosy, Sep 2014 - Present
Full-time Lecturer, Department of Medicinal Chemistry and Pharmacognosy, Sep 2013 - Sep 2014

Analytical Manager, PRU, Jordan, Jan 2007- Jan 2008
Analytical Scientist , GlaxoSmithKline (GSK- Europe), United Kingdom, Jan 2005- Jan 2006
Analytical Scientist , Pfizer R & D , United Kingdom, Jan 2004- Jan 2005

ANALYTICAL TECHNIQUES IN DRUG DISCOVERY
CHROMATOGRAPHY
COMMUNITY PHARMACY (FOR PHARM.D STUDENTS)
INSTRUMENTAL ANALYSIS
PHARMACEUTICAL PRACTICAL TRAINING
PHARMACEUTICAL ANALYTICAL CHEMISTRY
PHARMACEUTICAL ANALYTICAL CHEMISTRY & INSTRUMENTAL ANALYSIS LAB
PHARMACEUTICAL INSTRUMENTAL ANALYSIS
PHARMACEUTICAL INSTRUMENTAL ANALYSIS LAB
Pharmaceutical Instrumental Analysis (for Pharm D students)
RESEARCH METHODOLOGY
SELECTED TOPICS ( 1)
SELECTED TOPICS ( 2)
SPECIAL TOPICS (B)
SPECIAL TOPICS (C)

جامعة العلوم والتكنولوجيا الأردنية

ص.ب. 3030, إربد 22110, الأردن

+ 962 2-7201000 :هاتف أرضي
+ 962 2-7095123 :فاكس

البريد الإلكتروني: public@just.edu.jo