Studying disease mechanisms at the molecular and cellular level through description of the genes involved, the genetic lesions they suffer and the function of the proteins they specify in relation to the pathology of the disease(s) in which they are implicated. Discussion will include Oncogenes and tumour suppressor genes dealing with their identification and function, tyrosine kinases, transcription factor oncogenes, the role of chromosome translocations in oncogene activation and involvement of oncogenes/tumour suppressor genes in control of the cell cycle. In addition, The regulation of cell division dealing with cell cycle kinetics, transformation, gap junctions and signal transduction.