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Department Compulsory Req. (16) Hours:

Department Elective Req. (9) Hours:

Specialization Compulsory Req. (9) Hours:

Course Description:

Advanced Pharmacology (M 752):

In this mandatory course the basic principles of drug action in terms of the sites and mechanisms will be covered. Special concerns will be directed towards drug action on the central and peripheral nervous system and effector tissue, the kidneys, and cardiovascular and endocrine systems. Pathophysiologic states, which justify the use of these agents, are discussed. Additionally, adverse reactions and toxicities are identified.

Applied Pharmacokinetics (M 753):

The primary goals of this course are designed to provide the student with rigorous and practical concepts in applying pharmacokinetic methods, pharmacodynamic principles, and relevant data to optimize patient therapy. The instructors will provide materials to serve a dual purpose. One aim is to review and critique the major pharmacokinetic and pharmacodynamic principles, which govern the use of special drugs and/or the major physiologic factors, illnesses and drug interactions affecting drug absorption, disposition, and efficacy. A second aim is to assemble and critically review the relevant literature for information to assist students requiring a current database and reference source.

Pharmacogenetics (M 754):

 This course will focus and deal with genetically caused variations in drug response, which are basically attributed either to drug metabolism or drug-receptor interaction. Emphasis will be directed to pharmacogenetic conditions in humans transmitted by genes affecting drug absorption, distribution, metabolism, excretion, and receptor action. Selected studies dealing with pharmacogenetics will be reviewed, and methods and tests employed in the screening of population to ascertain how a particular trait is inherited will be evaluated. Group discussion will be conducted to review and evaluate published data dealing with the frequency of genes controlling various traits among different races and populations in various geographical areas in the world.

Fundamentals of Toxicology (M 755):

This course will be organized to facilitate coverage of various disciplines in toxicology. A focus will be directed on the elements of method and approach that identify toxicology. It will include the principles most frequently invoked in a full understanding of toxicology events, such as dose-response, and its primary mechanistic orientation. Mechanisms of various toxicants will be stressed, particularly when these are well identified. Another focus will be directed to the systemic site of action of toxins with the intention to provide answers to two basic questions: what kinds of injury are produced in specific organs or systems by toxic agents? What are the agents that produce these effects?

Neuropharmacology (M 757):

This course covers the principles of physiology of excitable cells and pathophysiology of the central and peripheral nervous system. Special emphasis will be directed toward the etiology of neurological diseases as possible target sites of therapeutic agents. This graduate course will include study of mechanisms of action of various drugs acting on the central nervous system.

Special Topics in Pharmacology (M 758):

The course includes a discussion of original publications focusing on the pharmacology of various systems, as well as an introduction to pharmacokinetics and the relationship between pharmacokinetics and pharmacodynamics. Critical review of pharmacology literature will be based on the analysis and appraisal of selected publications.

Experimental Techniques in Pharmacology and Physiology (M 759):

Topics include fundamentals of animal handling, surgical procedures in small animals, techniques of drug administration via various routes, collection of blood samples in live animals, and various tissues from killed animals. The graduate student will be trained to design experimental protocols appropriate for target investigations. Various drug assay techniques will be covered including drug concentration analysis using chromatographic procedures, such as thin layer and high performance liquid chromatography (HPLC).

Advanced Anatomy and Cell Biology (M 710):

This course covers the knowledge of the gross anatomy of the human body. This course is designed to assist the students to understand the basic concepts, the terminology and macroscopic structure with detailed dissection of the parts that form the different systems of the human body and relate this anatomical information to their clinical applications. This course also covers the structure of the cell and the different types of tissues.

Biochemistry (M 721):

Advanced comprehensive study of the molecular organization, Structure function and bio-energetic principles of biomolecules amino acids, proteins, enzymes, carbohydrates, lipids and nucleic acids. Emphasis is on the structure-function relationships, solution behavior and metabolism of biomolecules.

Advanced Molecular Biology (M 722):

Advanced comprehensive study of the molecular organization, properties, and physiological functions of genetic material. In addition, a complete description of general methods for genetic manipulation including restriction analysis, cloning vectors, library construction, Southern blots, and polymerase chain reaction. Applications to biotechnology include over-expression, transgenic organisms, DNA diagnostics, and gene therapy.

Advanced Physiology (M 730):

This course is designed to provide graduate students with depth understanding of the principles related to physiology as a study of the living body at molecular, cellular as well as the level of intact organism. Fundamentals of physiological principles and the concept of internal environment and homeostasis, some examples of homeostatic mechanisms of the major functional systems and various control systems that are utilized by different organs to regulate various physiological are emphasized. The functions of the nervous, endocrine, digestive, circulatory, respiratory and urinary system are discussed.

Experimental Design & Biostatistics (M 740):

The aim of the course is to cover the subject of descriptive and inferential statistics. It deals with Bayes theorem application in health fields. Estimation of confidence interval and hypothesis testing like (Z), (t) and (chi- square) tests.  After reviewing the advantages of each type of health research, the clinical trials are emphasized.

Seminar (M 790):

In this course, the student is required to review and prepare a selected topic in basic medical sciences (Pharmacology, Physiology, Anatomy and Biochemistry and Molecular Biology) and to present it to the staff members and other graduate students in the department. The presented topic will be evaluated comprehensively, and the student should submit the written copy of the presented material for farther evaluation.

Teaching skills (M 763):

In this course, the student is trained various teaching skills and methods to achieve best way learning objectives for audients. The graduate student is introduced to teaching skills by being asked to prepare and deliver selected lectures to medical students and paramedical students in basic medical sciences (Pharmacology, Physiology, Anatomy and Biochemistry and Molecular Biology)

Independent Study (M 760):

In this course, the students required coordination with a staff member, to make an extensive literature review about a specific topic in basic medical sciences (Pharmacology, Physiology, Anatomy and Biochemistry and Molecular Biology). Following this review, he should select a proposed study, and write a thesis proposal including the aims, the methods, the expected results, and the conclusions. The research proposal should be presented orally in the department.

Laboratory skills (M 764):

In this practical course, the student participates actively in the teaching laboratory of the Medical School, which includes pharmacology, biochemistry, physiology, anatomy, microbiology, and pathology.