This course covers the principles of the pharmacology of the central nervous system and the pathophysiology of the peripheral and central nervous systems. Special emphasis will be directed towards the etiology of the neurological diseases as possible target sites of therapeutic agents. This graduate course will include study of mechanisms of action of various drugs acting on the central nervous system in correlation with the pathogenesis of the disease process affecting the central nervous system.
This course is designed to provide the graduate students in pharmacology with basic and clinical knowledge in neuropharmcology. Pathophysiologic states which justify the use of various classes of drugs will be discussed. Students will be expected to participate actively in group discussion and debate different therapeutic approaches and demonstrate through structural discussion both the principles and objectives of pharmacological management of various neurological disorders.
Text and Reading materials:
1. The Pharmacological Basis of Therapeutics.
Goodman and Gilman's, 10th edition, Mc Grow Hill, 2001.
2. Basic and Clinical Pharmacology.
B. G. Katzung, 7th edition, Appleton and Lange, 1998.
H. P. Rang, M. M. Dale, J. M. Ritter and P. K. Moore 5th edition, Churchill Livingstone, 2003.
4. Modern Pharmacology with Clinical Applications
C. R. Craig and R. E. Stitzel, 6th edition, Lippincott Williams and Wilkins, 2004.
5. Clinical Pharmaclogy
D. R. Laurence, P. N. Bennett and M. J. Brown,
8th edition, Chaurchill Livingstone, 1997.
II. Selected web sites:
III. Selected journals dealing with neuropharmacology and neurosciences.
1. Selected topic presentation and report submission (60% of the final grade).
2. Final oral and written examinations (40% of the grade).