This course will focus and deal with genetically caused variations in drug response, which are basically attributed either to drug metabolism or drug-receptor interaction. Emphasis will be directed to pharmacogenetic conditions in humans transmitted by genes affecting drug absorption, distribution, metabolism, excretion, and receptor action. Selected studies dealing with pharmacogenetics will be reviewed, and methods and tests employed in the screening of population to ascertain how a particular trait is inherited will be evaluated. Group discussion will be conducted to review and evaluate published data dealing with the frequency of genes controlling various traits among different races and populations in various geographical areas in the world.
