Jordan University of Science and Technology

Faculty of Pharmacy

Department of Pharmaceutical Technology

Pharmacy Practice Lab I

Lab 10

Preparation of simple linctuses

Objectives:

 

1- Preparation of a simple linctus solution.

2- Perform literature search for therapeutic information related to a given medicated syrup.

3- Practice patient counseling.

4- Revision of vital signs.

 

Introduction:

 

Linctuses are viscous, liquid oral preparations that are usually prescribed for the relief of cough. They usually contain a high proportion of syrup and glycerol which have a demulcent effect on the membranes of the throat. The dose volume is usually small (5 ml). In order to prolong the demulcent action, they should be taken undiluted and should be labeled by

 to be swallowed slowly without the addition of water”.

     

Syrups are concentrated aqueous solutions of a sugar usually sucrose in water or other aqueous polyols like glycerol or Sorbitol. When purified water alone is used in making the solution of sucrose, the preparation is known as syrup or simple syrup. Syrups also could contain other polyols such as glycerol, Sorbitol, alcohol and flavored substances. Syrups as such are not intended to be administered as such but are used as a vehicle for other ingredient because of its flavoring and sweetening properties.

 

Experimental

Rx 50 ml simple linctus formula

 

Citric acid monohydrate…….1.25 g

Amaranth solution…………..0.08 ml

Chloroform spirit…………….3.0 ml

Flavor………………………...q.s.

Syrup        q.s…………………50 ml

 

 

Labeling:

Store in constant temperature not exceeding 25 C 0

Shelf life one month

For oral use, to be sipped and swallowed slowly without the addition of water

Color of print is black

 

Important notes for administration of liquids using oral syringes:

 

 

  1. Fill the syringe with the required dose.
  2. With the syringe pointed up, tap it lightly to dislodge any air bubbles. Then push the plunger until it lines up with the appropriate marking.
  3. Children or adult patients should sit upright while the medication is administered. Cradle an infant in your arms with the head and shoulders elevated and press gently on the chin to open the mouth.
  4. Direct the syringe toward the inside of the cheek and gums near the back of the mouth. To prevent choking and drooling, press the syringe plunger slowly and administer the dose in several small portions, allowing the patient to swallow each portion. Gently stroke the outside of an infant’s throat to promote swallowing. Do not lay an infant down until the entire dose has been swallowed.
  5. Pull the plunger out of the syringe, rinse the syringe and plunger thoroughly with warm tap water, allow them to dry, and reassemble the syringe.